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National Institute of Research and Development for Biological Sciences

Identification and characterization of biologically active compounds with antioxidant properties from natural bio(re)sources

Description

The objective of this theme was the identification and characterisation of natural resources as a basis for the superior valorisation of biologically active compounds with antioxidant properties, with a view to their potential use in food supplements or innovative phytopharmaceutical formulations. We obtained and characterised isoflavone-concentrated phytocomplexes using an original extractive technology - membrane technology, based on selective separation processes. Hydroalcoholic extracts were obtained and processed by membrane methods: micro- and ultrafiltration. We succeeded in developing an original technology integrating membrane processes in order to obtain isoflavonoid-concentrated phytocomplexes with potential in the management of metabolic diseases.
A study of the action of the obtained phytocomplexes on some enzymes involved in the pathology of diabetes was performed. The obtained results demonstrated that the concentrated extracts can be exploited as promising sources in the management of type 2 diabetes mellitus.