This theme aimed to assess the bioremediation potential (soil and coloured wastewater) of bacterial strains from different terrestrial ecosystems in the RBDD. A collection of bacteria with multiple biotechnological potential from the RBDD (novel character) was envisaged. From the ecological point of view, the investigation of natural and variously anthropogenised impoundments was approached in order to characterise and assess their vulnerability in the current context of climatic extremes and anthropogenic pressure. Twelve bacterial strains with bioremediation potential for synthetic dyes were identified and selected. The integration of the results in the field of microbial biotechnology led to the selection and introduction in the collection of 33 bacterial strains from different natural/anthropised terrestrial ecosystems of the RBDD. The results obtained consisted in ecophysiological researches in the perimeter of the Danube Delta Biosphere Reserve.