Alice-Georgiana Stoica
Research Assistant - Bioanalysis Center
Biography
I graduated from the Faculty of Biology, Department of Biochemistry, at the University of Bucharest, in 2021, presenting a thesis focused on the similarities between the intestinal and blood-brain barriers, their interaction, and the importance of dysbiosis in the development of neuroinflammatory and neurodegenerative diseases.
In my search for continuous professional development, I then pursued a Master in Applied Genetics and Biotechnology, also at the University of Bucharest, which I completed in 2023. The master thesis was dedicated to the analysis of the genotoxicity of Ag and ZnO nanoparticles used in the manufacture of biomaterials for medical utensils with the aim of reducing nosocomial infections, a particularly relevant and current research field.
During my years of study and internships at various institutes and laboratories I have acquired skills in the use of numerous techniques and methods including electrophoresis, PCR, Western blot, chromatography, microscopy and cell culture.
Publications
| Publication | Authors | data | |
|---|---|---|---|
article
N-Doped Nanocrystalline Graphite Electrochemical Sensor For Oleuropein Detection From Extra Virgin Olive Oils |
Albu Camelia; Chira Ana; Stoica Alice; Radu Gabriel-Lucian; Radoi Antonio; Stoian Marius; Simionescu Octavian-Gabriel; Eremia Sandra A. V. | Chemosensors, 2024 | |
AbstractA nitrogen-doped nanocrystalline electrochemical graphite sensor for the sensitive determination of oleuropein (OL) from extra virgin olive oils (EVOOs) is presented. The sensor was developed by the deposition of nanocrystalline graphite (NCG) using plasma-enhanced chemical vapour deposition (PECVD) on silicon wafers. Scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDX) and X-ray diffraction analysis (XRD) were used to characterise the microstructure and morphology of the developed materials. Cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and square wave voltammetry (SWV) were used to investigate the electrochemical properties of the material and the performance of the sensor. The developed sensor showed good analytical performance against OL over a concentration range of 5.00-500.00 mu M, with a good detection limit of 3.93 mu M and a good sensitivity of 0.057 mu A mu M-1. The reproducibility of the electrochemical sensor was excellent, with a relative standard deviation (RSD) of 8.56% for seven measurements. |
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article
Winemaking Technologies For The Production Of Cabernet Sauvignon And Feteasca Neagra Wines Enriched With Antioxidant Active Principles Due To The Addition Of Melatonin |
Eremia Sandra A. V.; Albu Camelia; Radu Gabriel-Lucian; Alecu Andreia; Stoica Alice G.; Brinduse Elena | Foods, 2024 | |
AbstractIn recent years, various studies have been carried out to increase the concentration of antioxidant active principles in red wines as a consequence of the effects of winemaking techniques on the polyphenols content. In this study, in order to obtain the most optimal wine in terms of content and efficiency of antioxidant activity, various winemaking technologies (punching-down and pumping-over maceration) were tried with diverse gradations (Feteasca Neagra and Cabernet Sauvignon wines) and the addition of different concentrations of melatonin in must. Suitable HPLC and spectrophotometric methods were used to follow the evolution of the antioxidant compounds from wines during aging (for 12 months). After comparing the acquired results, an increase was observed in the antioxidant compound concentrations, particularly in resveratrol (85%), peonidin-3-glucoside (100%) or cyanidin-3-glucoside (100%), and antioxidant activity (10-40%). The most enriched wine was obtained in the case of Feteasca Neagra by the addition of 0.5 mg of melatonin per 1 kg of must using the punch-down technology and, in the case of Cabernet Sauvignon, by the addition of 0.05 mg of melatonin per 1 kg of must using the pumping-over technique. This study can provide winemakers with an approach to enhance red wines with antioxidant compounds. |
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article
Proposal For The Inclusion Of Two Active Raised Bogs In The Rosci0116 Molhașurile Căpățânei Protected Area Of Community Interest; [Propunere Pentru Includerea A Două Mlaștini Oligotrofe În Aria Protejată De Interes Comunitar Rosci0116 Molhașurile Căpățânei] |
Stoica A.-I.; Ciobanu M.; Şuteu D.; Coldea G. | Contributii Botanice, 2022 | |
AbstractOligotrophic peat bogs reach the southern boundary of their European distribution area in the Romanian Carpathians. They shelter boreal species considered glacial relicts, surviving from the Würmian III period. Such areas (habitats) conserving relict species have major phytohistorical importance. They provide insights into the history of forest vegetation in the region and past climatic conditions. Based on floristic, phytocoenological and phytogeographical data, we propose to include two active raised bogs, namely “Calul de Piatră” and “Izvorul văii Șoimului” in the ROSCI0116 Molhașurile Căpățânei site of community interest. The inclusion of the two bogs in the ROSCI0116 Molhașurile Căpățânei protected area will increase the peat bog surface in the Apuseni Mountains and will be beneficial for the conservation of the wetland habitats and their typical flora, both very vulnerable to natural and anthropogenic disturbances. © 2022, Babes-Bolyai University, "Alexandru Borza" Botanic Garden. All rights reserved. |
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article
Integrating Demography And Distribution Modeling For The Iconic Leontopodium Alpinum Colm. In The Romanian Carpathians |
Maghiar Lacramioara M.; Stoica Ilie A.; Tanentzap Andrew J. | Ecology And Evolution, 2021 | |
AbstractBoth climate change and human exploitation are major threats to plant life in mountain environments. One species that may be particularly sensitive to both of these stressors is the iconic alpine flower edelweiss (Leontopodium alpinum Colm.). Its populations have declined across Europe due to over-collection for its highly prized flowers. Edelweiss is still subject to harvesting across the Romanian Carpathians, but no study has measured to what extent populations are vulnerable to anthropogenic change. Here, we estimated the effects of climate and human disturbance on the fitness of edelweiss. We combined demographic measurements with predictions of future range distribution under climate change to assess the viability of populations across Romania. We found that per capita and per-area seed number and seed mass were similarly promoted by both favorable environmental conditions, represented by rugged landscapes with relatively cold winters and wet summers, and reduced exposure to harvesting, represented by the distance of plants from hiking trails. Modeling these responses under future climate scenarios suggested a slight increase in per-area fitness. However, we found plant ranges contracted by between 14% and 35% by 2050, with plants pushed into high elevation sites. Synthesis. Both total seed number and seed mass are expected to decline across Romania despite individual edelweiss fitness benefiting from a warmer and wetter climate. More generally, our approach of coupling species distribution models with demographic measurements may better inform conservation strategies of ways to protect alpine life in a changing world. |
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article
The Distribution And Behaviour Studies On A New Invasive Buprestid Species, Lamprodila Festiva (Coleoptera: Buprestidae) In Romania |
Ruicănescu A.; Stoica A.-I. | Travaux Du Museum National D'Histoire Naturelle Grigore Antipa, 2019 | |
AbstractThe Cypress Jewel Beetle (Lamprodila (Palmar) festiva subsp. festiva (Linnaeus 1767)), is a formerly rare and protected species, present in the red lists of most Western European countries. In Romania, before 2015 it was present only in the South-Western region and less than 10 specimens were collected. The species recently changed its host plants from wild Cupressaceae (Juniperus sp., Cupressus sp.) to cultivated Cupressaceae, the most affected one being Thuja occidentalis. In 2013 the first big invasion was recorded in Budapest, Hungary. In 2015, the species was found in two horticultural seedling stations in Bucharest. More recently, in 2017, it was recorded in Cluj-Napoca, and in 2018, in Timișoara, Oradea, Suceava. The article provides a short description of the adults, larva and the signs of the attacks on the host plants. The potential distribution of the species is discussed based on climate niche modelling. The daily behaviour of the adults and their preferences, based on observations, is also discussed. Equally, the bioethics related to this attack is analysed. Copyright Ruicănescu & Stoica. |
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