Daniela Florea
Research Assistant - Bioinformatics
Publications
Publication | Authors | data | |
---|---|---|---|
conference
Multifaceted Phenotypic Adaptations Of Gammarus Balcanicus To Caves: Hypogean Versus Epigean Ecotypes |
Octavian Pacioglu Daniela Florea Iris Tusa | Conferinta Aquatic Biodiversity International Conference, 2024 | |
Abstract |
|||
conference
Ecophysiological And Life – History Adaptation Of Gammarus Balcanicus (Schaferna, 1922) In A Sinking – Cave Stream From Western Carpathians (Romania) |
O. Pacioglu; I. M. Tușa; M. Sidoroff; D. Florea; G. Gavril; C. Ițcuș | The 7Th International Conference Ecological And Environmental Chemistry, Chisinau, Republic Of Moldova, 2022 | |
Abstract |
|||
conference
Pshysico – Chemical And Microbiological Assessment Of Waters And Sediments From Danube Delta |
C. Itcus; I. Tusa; O. Pacioglu; D. Florea; G. Gavril; M. Sidoroff; C. Coman | The 7Th International Conference Ecological And Environmental Chemistry, Chisinau, Republic Of Moldova, 2022 | |
Abstract |
|||
article
How Accurate Is The Remote Sensing Based Estimate Of Water Physico-Chemical Parameters In The Danube Delta (Romania)? |
Necula Marian; Tusa Iris Maria; Sidoroff Manuela Elisabeta; Itcus Corina; Florea Daniela; Amarioarei Alexandru; Paun Andrei; Pacioglu Octavian; Paun Mihaela | Annals Of Forest Research, 2022 | |
AbstractThe current paper estimated the physico-chemical properties of water in the Danube Delta (Romania), based on Sentinel 2 remote sensing data. Eleven sites from the Danube Delta were sampled in spring and autumn for three years (2018-2020) and 21 water physico-chemical parameters were measured in laboratory. Several families of machine learning algorithms, translated into hundreds of models with different parameterizations for each machine learning algorithm, based on remote sensing data input from Sentinel 2 spectral bands, were employed to find the best models that predicted the values measured in laboratory. This was a novel approach, reflected in the types of selected models that minimised the values of performance metrics for the tested parameters. For alkalinity, calcium, chloride, carbon dioxide, hardness, potassium, sodium, ammonium, dissolved oxygen, sulphates, and suspended matter the results were promising, with an overall percentage bias of the estimates of +/- 10% from the observed values. For copper, magnesium, nitrites, nitrates, turbidity and zinc the estimates were fairly accurate, with percentage biases in the interval +/- 10% - 20%, whereas for detergents, led, and phosphates the percentage bias was higher than 20%. Overall, the results of the current study showed fairly good estimates between remote sensing based estimates and laboratory measured values for most water physico-chemical parameters. |
|||
article
Network Analytics For Drug Repurposing In Covid-19 |
Siminea Nicoleta; Popescu Victor; Martin Jose Angel Sanchez; Florea Daniela; Gavril Georgiana; Gheorghe Ana-Maria; Itcus Corina; Kanhaiya Krishna; Pacioglu Octavian; Popa Laura Lona; Trandafir Romica; Tusa Maria Iris; Sidoroff Manuela; Paun Mihaela; Czeizler Eugen; Paun Andrei; Petre Ion | Briefings In Bioinformatics, 2022 | |
AbstractTo better understand the potential of drug repurposing in COVID-19, we analyzed control strategies over essential host factors for SARS-CoV-2 infection. We constructed comprehensive directed protein-protein interaction (PPI) networks integrating the top-ranked host factors, the drug target proteins and directed PPI data. We analyzed the networks to identify drug targets and combinations thereof that offer efficient control over the host factors. We validated our findings against clinical studies data and bioinformatics studies. Our method offers a new insight into the molecular details of the disease and into potentially new therapy targets for it. Our approach for drug repurposing is significant beyond COVID-19 and may be applied also to other diseases. |
|||
conference
The Effects Of Climatic Conditions On The Human Body Regarding Erythrocyte Viability |
Iris Tușa; Ana-Maria Gheorghe; Daniela Florea; Corina Ițcuș | Life Quality: Assessments, Approaches And Perspectives” Moeciu, Brașov, Romania, 2021 | |
Abstract |
|||
conference
Response Of Aquatic Invertebrates To Eutrophica-Tion |
Octavian Pacioglu; Daniela Florea; Corina Ițcuș | Life Quality: Assessments, Approaches And Perspectives” Moeciu, Brașov, Romania, 2021 | |
Abstract |
|||
conference
Network Controllability Analysis For Drug Repurposing In Covid-19 |
Nicoleta Siminea; Victor Popescu; Jose Angel Sanchez Martin; Ana-Maria Dobre; Daniela Florea; Geor-giana Gavril; Corina Ițcuș; Krishna Kanhaiya; Octavian Pacioglu; Laura Ioana Popa; Romica Trandafir; Maria Iris Tușa; Manuela Sidoroff; Mihaela Păun; Eugen Czeizler; Andrei Păun; Ion Petre | The 29Th Conference On Inteligent Systems For Molecular Biology, Joint With The 20Th European Conference On Computational Biology, 2021 | |
Abstract |